Just opening this up for discussion, but in my opinion the real cure here is for you to really align yourself with some people in a close relationship. It will require you to be vulnerable and open with others, something unnatural and unpleasant but necessary in order to build friendship.

You are feeling low in general because you’re not receiving enough feedback of being wanted/needed in a group setting frequently enough. This general low mood is the body’s way of almost hibernating I think, it’s like it’s in rest mode and saving energy for when it’s needed. Notice how the body doesn’t shock us into a heightened state of at the fact we’re facing loneliness or are distant from a tribe etc. Regardless, I think trying to expand your circle is all you can do.

Either way my best wishes.

B