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Reply To: Too Criticizing of Myself

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#344794
Janus
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Another interesting thing about the current coronavirus from “Mutations can reveal how the coronavirus moves—but they’re easy to overinterpret” article from sciencemag.org :

“Over the length of its 30,000-base-pair genome, SARS-CoV-2 accumulates an average of about one to two mutations per month, Andrew Rambaut says. “It’s about two to four times slower than the flu.””

 

Since the coronavirus mutates slower, this allows researchers to sequence the viral genome much easier. It also allows researchers to make connections between different people who get infected by the coronavirus.

 

According to “UCSC genome browser posts the coronavirus genome” article (University of California- Santa Cruz, link eurekalert.org) :

the coronavirus genome consisting of a single-strand RNA has been analyzed using a Genome Browser that provides a visual representation of the coronavirus genome. The Genome Browser allows researchers to zoom in and out of the genome and they have discovered that the coronavirus has approximately 10 individual genes and comprises  29,903 base pairs.  The researchers have discovered that amongst the ten individual genes, the largest is the spike protein on the virus’s outer membrane which the virus uses to snag onto human cells and then enter the human cell to make more virus cells. Scientists are working on using CRISPR* to see if they can target specific sequences  in the virus’s genome and understand how certain genes work or how to make certain genes inactive in the virus which might lead to the virus being less virulent (less severe or harmful).

“UCSC genome browser posts the coronavirus genome” Feb. 7, 2020 article.

 

*[CRISPR is a tool that allows scientists to target a specific genetic sequence and then make a cut in the DNA or genome. Some uses for CRISPR currently are scientists  working on using CRISPR to manipulate specific genes such as using it to knock out a gene (making it inactive) and possibly repair a mutation by replacing the mutated gene with a healthy one.]

 

  • This reply was modified 4 years, 8 months ago by Janus.