Dear Eric

The more you understand your body and its needs and how it influences your judgement and how your brain, mind etc work and influence your body you will be able to see that when you make decisions that are in line with your best self the better you will feel about them.  Learning to let go of the outcome ( & possible outcomes of decisions) or control of the outcome eases ones mind.  In general I do not find secrets helpful as  it often generates fear. living ones life clearly & honestly, being open to myself & others brings more joy and yes life will always bring loss of some kind but that is reality of impermanence that we (all things ) are subject to.